Seven years ago, biochemist Zheng Cui of Wake Forest University was conducting a routine experiment, injecting test mice with a strain of cancer cells so aggressive it caused a 100 percent death rate. Oddly, one of the mice wouldn't die. Thinking he had made an error, Cui injected the mouse with a million times the lethal dose, but it still lived.
Cui was intrigued. He bred the mouse and found that 40 percent of its offspring share a remarkable resistance to many forms of cancer. When the animals' immune systems identify a cancer cell, a genetic tweak allows their bodies to launch a massive attack of white blood cells that kills the budding tumor.
Now Cui and his colleagues have found a clue that may point the way to an actual cure. When they inject white blood cells from any of these anticancer mice into their nonresistant brethren, the injected ...
