The Top 10 Science Experiments of All Time

These seminal experiments changed our understanding of the universe and ourselves.

By Adam Hadhazy
Oct 10, 2019 4:22 PMDec 13, 2019 3:47 PM
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(Credit: Mark Marturello)

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Every day, we conduct science experiments, posing an “if” with a “then” and seeing what shakes out. Maybe it’s just taking a slightly different route on our commute home or heating that burrito for a few seconds longer in the microwave. Or it could be trying one more variation of that gene, or wondering what kind of code would best fit a given problem. Ultimately, this striving, questioning spirit is at the root of our ability to discover anything at all. A willingness to experiment has helped us delve deeper into the nature of reality through the pursuit we call science. 

A select batch of these science experiments has stood the test of time in showcasing our species at its inquiring, intelligent best. Whether elegant or crude, and often with a touch of serendipity, these singular efforts have delivered insights that changed our view of ourselves or the universe. 

Here are nine such successful endeavors — plus a glorious failure — that could be hailed as the top science experiments of all time.

Eratosthenes Measures the World

Experimental result: The first recorded measurement of Earth’s circumference 

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