The 5 Most Important Scientific Equations of All Time

Calculating the most influential scientific equations is no easy task. But these five certainly rank in the top tier.

By Nathaniel Scharping
Apr 15, 2021 5:00 PMOct 24, 2024 1:20 PM
scientific formulas on a chalkboard - shutterstock 1698478423
(Credit: I000s_pixels/Shutterstock)

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What’s in an equation? Letters and numbers and odd symbols — but also a novel insight into the relationships between fundamental constituents of our physical reality. All equations crystallize something important about the universe, whether it be the relationship between mass and energy, the gravitational attraction between two bodies or the sides of a triangle.

The most important part of any equation is the equals sign at its heart. Those two horizontal lines tell us that when we change one thing, we’ll see a corresponding change in another, apparently separate thing. In this way, equations reveal the connections between superficially different quantities or properties. Once linked together, that newly discovered relationship can serve as the basis for future insights.

To pick the most important equations is an almost hopeless task. The importance of any given relationship will differ greatly depending on the context. If you are falling out of an airplane, for example, the law of gravitation will feel much more significant than will the Schrödinger equation. SImilarly, equations are of different importance to scientists depending on the field they are in. 

But it is possible to pick out a few equations that have had an outsize influence on the way we see the world. While it’s not an exhaustive list, these five equations all summarize something brand new — whether it be a new relationship between things, or just a new way of looking at the world. And once set down on paper, these equations all enabled future breakthroughs as generations of thinkers used their powers to make new discoveries.

1. E=mc^2

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