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A Beginner's Guide To Cloning

Despite logistical and ethical hurdles, the ability to create genetic replicas could aid medical research and possibly save animals from extinction.

A taxidermy of the sheep clone Dolly on display at the National Museum of Scotland.Credit: Jordan Grinnell/Shutterstock

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In 1996, one of the most famous instances of cloning occurred when Dolly was made from the udder cell of a 6-year-old sheep. But what exactly is cloning? It’s broadly defined as “the creation of an exact genetic replica of a small segment of DNA, a cell or a whole organism.” However, the resulting creature isn’t always a carbon copy of its source. The genetic outcome depends on the specific method employed. Scientists conduct three different types of cloning:

In a method perhaps less exciting than that which led to Dolly’s conception, gene or molecular cloning creates copies of genes or DNA segments. It’s often used to study particular genes in a lab.

In this case, scientists take a specific DNA segment and place it in the self-replicating genetic material called plasmid DNA within a bacterial cell. They then put the resulting recombinant (combined human and bacterial) DNA into a ...

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