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Regulating the Brave New World of Human Gene Editing

Ethics in a post-CRISPR-Cas9 society.

ByPaul Smaglik
A human embryo days after in vitro fertilization. The U.K. has approved CRISPR gene editing on human embryos.Credit: Zephyr/Science Source

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As the prospect of humans who have been genetically cut and pasted moves closer to reality, governments have begun to take notice of the need for regulation.

Through the recently developed gene-editing tool CRISPR-Cas9, scientists can now tweak DNA with unprecedented speed and precision.

In 2015, Chinese scientists announced they had used CRISPR-Cas9 on human embryos for the first time. The project, though unsuccessful, took many researchers and governments by surprise and set off a global discussion about the legal and ethical implications of the research.

(Credit: Alison Mackey/Discover after Genome Research Limited)

Alison Mackey/Discover after Genome Research Limited

“[The experiment] was actually quite fortunate in a way,” says Katherine Littler, policy adviser at the British medical research charity Wellcome Trust. “We need to have debates about how these things should be regulated.”

In February, the United Kingdom approved using the method on human embryos at the Francis Crick Institute ...

  • Paul Smaglik

    Before joining Discover Magazine, Paul Smaglik spent over 20 years as a science journalist, specializing in U.S. life science policy and global scientific career issues. He began his career in newspapers, but switched to scientific magazines. His work has appeared in publications including Science News, Science, Nature, and Scientific American.

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