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Rats Facing Lego Robot Scorpions May Help Understand Human Anxiety

Recording neuron activity associated with different objects can show how nervousness related to specific locations or objects persists.

ByPaul Smaglik
A rat peeking around a corner is concerned about the robot at the end of the hall.Credit: Redish Lab, University of Minnesota

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If you’ve ever had a bad experience with a particular place and, in the future, physically feel anxious as you approach it again, there’s a good reason: our brains may record and physically map that experience for future reference, a new study in PLOS Biology suggests.

This has implications for mental health, because it helps us understand how worry works.

“The more that we understand how the mechanisms by which cognition works, the better we can help people who have problems with their cognition,” says David Redish, a University of Minnesota neuroscientist and an author of the study. “Anxiety and worry are very prevalent in humanity these days.”

In the study, scientists devised a scenario where rats would have to encounter something very negative to them — a scary Lego robot scorpion — to reach a treat.

“Imagination is a physical thing,” says Redish. “And that includes not just imagination ...

  • Paul Smaglik

    Before joining Discover Magazine, Paul Smaglik spent over 20 years as a science journalist, specializing in U.S. life science policy and global scientific career issues. He began his career in newspapers, but switched to scientific magazines. His work has appeared in publications including Science News, Science, Nature, and Scientific American.

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