Stay Curious

SIGN UP FOR OUR WEEKLY NEWSLETTER AND UNLOCK ONE MORE ARTICLE FOR FREE.

Sign Up

VIEW OUR Privacy Policy


Discover Magazine Logo

WANT MORE? KEEP READING FOR AS LOW AS $1.99!

Subscribe

ALREADY A SUBSCRIBER?

FIND MY SUBSCRIPTION
Advertisement

Functioning, Lab-Grown Limb is a First

A dead rat's forearm is regrown in a lab and successfully transplanted onto a living rat.

Bernhard Jank, MD, Ott Laboratory, Massachusetts General Hospital Center for Regenerative Medicine

Newsletter

Sign up for our email newsletter for the latest science news

Sign Up

Dr. Frankenstein wishes he were this good: In June, Massachusetts General Hospital researchers announced they’d built the first functioning lab-grown limb. The team amputated a dead rat’s forearm and chemically stripped away living cells, leaving behind what’s called the extracellular matrix, a kind of scaffolding for everything from blood vessels to nerve networks. The limb then spent two weeks growing muscular and vascular cells in a custom-built bioreactor. Electrical stimulation showed the resulting limb had a grip strength 80 percent that of a newborn rat’s. After being transplanted onto a living rat, the limb circulated blood through its new vessels.

[This article originally appeared in print as "It's Alive! Well, Sort of."]

Stay Curious

JoinOur List

Sign up for our weekly science updates

View our Privacy Policy

SubscribeTo The Magazine

Save up to 40% off the cover price when you subscribe to Discover magazine.

Subscribe
Advertisement

0 Free Articles