Biologists Create Organism With Smallest Genome

Stripping life to the bare essentials.

By Jonathon Keats
Dec 22, 2016 6:00 AMNov 12, 2019 5:35 AM

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A variety of structures have been observed in the cultures of JCVI-syn3.0, the first minimal bacterial cell. | Thomas Deerinck and Mark Ellisman/NCMIR

The pathogenic bacterium Mycoplasma genitalium has only 525 genes, the fewest of any living organism. The concise creation was a favorite with geneticists, and it was one of the first organisms to be fully sequenced, a feat achieved in 1995 by biologist J. Craig Venter and his team.

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