Mind

The Appalachia rural West Virginia of Asia strikes again!

Gene ExpressionBy Razib KhanDec 14, 2006 5:11 PM

Newsletter

Sign up for our email newsletter for the latest science news
 

P-eter comments on the Pakistani family which can't feel pain. I remember in a genetics course once seeing the professor chart out a pedigree and calculate inbreeding coefficients and the expectation of the unmasking of deleterious alleles given certain matings. Now and then we would laugh nervously since of course real matings between individuals so closely related would be creepy and unethical...but Pakistan with its culture of cousin-loving down the generations makes the science possible in real life! Let a thousand deleterious recessives bloom across the landscape!1 - Remember that inbreeding is particular problematic in a society where cousin-marriage is normative because the coefficient increases as you sum across recent common ancestors, and in such society cousins are likely to be related by many different paths.

1 free article left
Want More? Get unlimited access for as low as $1.99/month

Already a subscriber?

Register or Log In

1 free articleSubscribe
Discover Magazine Logo
Want more?

Keep reading for as low as $1.99!

Subscribe

Already a subscriber?

Register or Log In

More From Discover
Recommendations From Our Store
Shop Now
Stay Curious
Join
Our List

Sign up for our weekly science updates.

 
Subscribe
To The Magazine

Save up to 70% off the cover price when you subscribe to Discover magazine.

Copyright © 2022 Kalmbach Media Co.