The Top Scientific Breakthrough of 2020: Understanding SARS-CoV-2 — and Then Developing Multiple Vaccines

Thanks to science, the end of the pandemic is finally in sight.

By David Pride, University of California San Diego
Dec 18, 2020 3:10 PMDec 18, 2020 3:11 PM
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(Credit: kostasgr/Shutterstock)

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SARS-CoV-2, the virus that causes the respiratory illness COVID-19, has killed approximately 2.2% of those worldwide who are known to have contracted it. But the situation could be a lot worse without modern medicine and science.

The last such global scourge was the influenza pandemic of 1918, which is estimated to have killed 50 million people at a time when there was no internet or easy access to long-distance telephones to disseminate information. Science was limited, which made it difficult to identify the cause and initiate vaccine development. The world is 100% more prepared for the current pandemic than it was 100 years ago. However, it has still affected our lives profoundly.

I am a physician scientist who specializes in the study of viruses and runs a microbiology laboratory that tests for SARS-CoV-2 infections. I’ve seen firsthand patients with severe COVID-19 illness and have dedicated myself to developing diagnostics for this disease. It’s a remarkable testament to science that a novel disease-causing virus has been discovered, the genetic material completely decoded, new therapies created to fight it and multiple safe and effective vaccines developed all within the span of a year – an accomplishment that the journal Science has pegged the breakthrough of 2020.

Most vaccines take 10-15 years to develop. Until now the fastest vaccine developed was against the mumps virus, which took four years. Now, in the midst of the SARS-CoV-2 pandemic, one vaccine is already authorized for use in the U.S., with a second close behind. Other vaccines have already been rolled out in countries across the globe.

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