New Therapy Could Help Heart Tissue Heal After Heart Attack

Although only tested in rats thus far, the polymer-based treatment could repair tissue that are impacted in a variety of diseases.

By Paul Smaglik
Apr 25, 2025 9:15 PMApr 25, 2025 9:40 PM
Treated tissue vs untreated tissue
Side by side comparison of heart muscle cells with and without treatment. Damage to the cells is shown in blue. On the left, tissue has been injected with saline and the damaged area is considerably larger. On the right, the issue was treated with the PLP platform and the damaged area is significantly smaller. (Image Credit: University of California San Diego/Northwestern University)

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Researchers developed a polymer-based therapy that can be injected following a heart attack that helps heart tissue heal. After administering it to rats, they demonstrated that it works up to five weeks later, they reported in the journal Advanced Materials.

Heart attacks are a major health issue in the U.S., with about 805,000 people a year experiencing them — the equivalent of one every 40 seconds. About 12 percent of people who experience a heart attack will die from it.

“Preventing heart failure after a heart attack is still a major unmet clinical need,” Karen Christman, a bioengineering professor at the University of California, Davis and an author of the study, said in a press release. “The goal of this therapy is to intervene very soon after someone suffers a heart attack to keep them from ultimately going into heart failure.”

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