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Health

Important papers on recent human evolution

Gene ExpressionBy Razib KhanSeptember 29, 2007 1:08 PM

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This post is more of a personal note...here are three papers that are really cool must reads: Williamson SH, Hubisz MJ, Clark AG, Payseur BA, Bustamante CD, et al. (2007) Localizing Recent Adaptive Evolution in the Human Genome. PLoS Genet 3(6): e90 doi:10.1371/journal.pgen.0030090 Voight BF, Kudaravalli S, Wen X, Pritchard JK (2006) A Map of Recent Positive Selection in the Human Genome. PLoS Biol 4(3): e72 doi:10.1371/journal.pbio.0040072 Tang K, Thornton KR, Stoneking M (2007) A New Approach for Using Genome Scans to Detect Recent Positive Selection in the Human Genome. PLoS Biol 5(7): e171 doi:10.1371/journal.pbio.0050171 E.T. Wang, G. Kodama, P. Baldi, R.K. Moyzis, Global landscape of recent inferred Darwinian selection for Homo sapiens, Proc. Natl. Acad. Sci. USA 103, 135-140 (2006). doi:10.1073/pnas.0509691102All 4 papers are Open Access! The statistical & computational techniques can be hard to follow sometimes, but these HapMap datasets are the tip of the iceberg, so get comfy and start learning if you want to be able to follow the blow-by-blow over the next few years.... P.S.: If you dig flies, read Evolgen.

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