He Became Depressed and His Sex Drive Disappeared. What Was the Cause?

‘Everything was fine’ for this salesman, but he couldn’t shake his funk. His hormones may have had something to do with it.

By Douglas G. Adler
Oct 5, 2020 5:00 PM
Vital Signs November 20 illustration
(Credit: Kellie Jaeger/Discover)

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This article appeared in the November 2020 issue of Discover magazine as "Beyond the Blues." Subscribe for more stories like these.


Reggie, a 30-year-old pharmaceutical salesman, appeared in my office one afternoon to follow up on his cholesterol levels and other routine bloodwork. While the tests were all normal, I noticed he seemed to be in a bit of a funk, for lack of a more scientific term. Ordinarily an upbeat and positive person, he seemed to be down in the dumps. When I asked if anything was going on at home or at work, he said everything was fine. Still, he couldn’t deny that he did not feel like himself.

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