Register for an account

X

Enter your name and email address below.

Your email address is used to log in and will not be shared or sold. Read our privacy policy.

X

Website access code

Enter your access code into the form field below.

If you are a Zinio, Nook, Kindle, Apple, or Google Play subscriber, you can enter your website access code to gain subscriber access. Your website access code is located in the upper right corner of the Table of Contents page of your digital edition.

Health

Being black as a state of mind

Gene ExpressionBy Razib KhanDecember 23, 2009 1:19 AM
Walter_Francis_White.png

Newsletter

Sign up for our email newsletter for the latest science news

A few days ago I pointed out that actors with visible Asian ancestry, such as Keanu Reeves, Mark-Paul Gosselaar and Dean Cain, can play white characters, while those with visible African ancestry can not (I will leave it to debate whether you think Rashida Jones or Jennifer Beals are violations of that rule or not). On the other hand, it does seem that people with no visible African ancestry can identify as black American due to the norm of hypodescent. For example, consider Walter White, who identified as a black man despite his visible white European appearance. White used his ability to "pass" during his long Civil Rights career since he could operate "undercover." One of the unsurprising things which modern genomics is uncovering is that though the median African American has European admixture on the order of ~20%, there is a wide variance. Consider this plot (I've reedited it a bit, the figure can be found in this paper) :

journal.pgen.1000294.g001.png

Note that one individual in the sample who was black identified is likely mostly European in ancestry. On this note, Dienekes points to a new study on African and African American genetics which concludes:

The rich mosaic of African-American ancestry. Among the 365 African-Americans in the study, individuals had as little as 1 percent West African ancestry and as much as 99 percent. There are significant implications for pharmacogenomic studies and assessment of disease risk. It appears that the range of genetic ancestry captured under the term African-American is extremely diverse, suggesting that caution should be used in prescribing treatment based on differential guidelines for African-Americans. A median proportion of European ancestry in African-Americans of 18.5 percent, with large variation among individuals.

If an individual is 1 percent African in ancestry, I would assume that a doctor would not make a decision guided by their social identification of group identity, as opposed to the genetic reality! But I've noticed drug guidelines which request that you tell your doctor if you are Asian, so who knows? Here's the press release for the paper alluded to above.

    2 Free Articles Left

    Want it all? Get unlimited access when you subscribe.

    Subscribe

    Already a subscriber? Register or Log In

    Want unlimited access?

    Subscribe today and save 70%

    Subscribe

    Already a subscriber? Register or Log In