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27: Frozen Ovary Restores Fertility

Ovarian tissue transplant enabled a cancer survivor in Belgium to give birth, offering hope against infertility from chemotherapy.

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In a world first, Ouarda Touirat, a 32-year-old cancer survivor in Belgium, delivered a healthy baby this year after undergoing an ovarian tissue transplant. The revolutionary procedure offers hope of fending off infertility from chemotherapy or radiation damage to the ovaries.

Before Touirat received chemotherapy for Hodgkin’s lymphoma seven years ago, her doctor recommended preserving pieces of her ovaries that might later be used to restore her fertility. The sample remained frozen until five years after Touirat’s treatment. In early 2003 Jacques Donnez at the Catholic University of Louvain, in Belgium, thawed and grafted some of the preserved tissue under one of Touirat’s ovaries. Eleven months later, Touirat conceived, and her daughter, Tamara, was born in September.

Doctors are confident that the birth is going to be the first of many using the technique, although some questions remain about whether the egg fertilized in Touirat’s pregnancy really came from the ...

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