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Planet Earth

NCBI ROFL: "Back and forth forever" (or, DIY poop therapy).

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Success of self-administered home fecal transplantation for chronic Clostridium difficile infection. "Clostridium difficile infection (CDI) can relapse in patients with significant comorbidities. A subset of these patients becomes dependent on oral vancomycin therapy for prolonged periods with only temporary clinical improvement. These patients incur significant morbidity from recurrent diarrhea and financial costs from chronic antibiotic therapy. We sought to investigate whether self- or family-administered fecal transplantation could be used to definitively treat refractory CDI. We report a case series (n=7) where 100% clinical success was achieved in treating these individuals with up to 14 months follow up."

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Thanks to Caryn for today's ROFL!

Photo: flickr/★Debs★

And in case you didn't get our title reference: Related content: Discoblog: NCBI ROFL: One rat, one cup. Discoblog: NCBI ROFL: Rectal impaction following enema with concrete mix. Discoblog: NCBI ROFL: Rectal oven mitt.

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