There are 100 trillion microbes that live in your body. Do you own them? Do they deserve the same protections as your own genes and cells? If someone genetically alters a microbe and claims that if you swallow it, it will let you lose weight, should that living germ be regulated as a drug? These are a few of the questions I mull in a piece
that appears in the Sunday Review section of today's New York Times. I've been writing a lot about the microbial world for a few years now, but only recently did I encounter a group of bioethicists who are now pondering what sort of ground rules we should set up to govern science and medicine as we gain understanding and power over the microbiome. Check it out.
If you're interested in reading more about all this, here are a few new papers (some free, some behind paywalls). The Human Microbiome Project: lessons from human genomics
: Trends in Microbiology (in press)
, Kieran O'Doherty, BMC Medical Genomics 4 (1), (07 Oct 2011) info:doi/10.1186/1755-8794-4-72
Community Health Care: Therapeutic Opportunities in the Human Microbiome
Justin Sonnenburg and Michael Fischbach, Science Translational Medicine 3 (78), April 13, 2011 info:doi/10.1126/scitranslmed.3001626
There will also be a book coming out next year edited by Rosamond Rhodes of Mount Sinai Medical School, but it's not on the radar just yet. For now, here's a powerpoint of a recent presentation from her research group (pdf)
[Image: Andrea Wan
for the New York Times]