29 Best Lion's Mane Supplements for 2023

By Amber SmithSep 3, 2023 5:00 AM
Elm and Rye


Sign up for our email newsletter for the latest science news

Disclosure: This post contains affiliate links. 

Lion's Mane mushroom has been used for centuries in Eastern medicine, but recently it has gained a lot of popularity due to its impressive health benefits. It is known for its ability to boost cognitive function and improve overall brain health. In addition, Lion's Mane can help support the immune system and reduce inflammation. 

If you're looking for ways to benefit from Lion's Mane mushroom, then you've come to the right place! Here you will find a list of the 29 best lion's mane supplements for 2023 along with more details about each brand so you can choose the best supplement for your current circumstances. 

29 Best Lion’s Mane Supplements for 2023

  1. Elm & Rye Mushroom Complex

  2. BATCH Brain Boost Mushroom Gummies

  3. Perpetua Life Li

  4. Stonehenge Health 

  5. Wild Foods Co 

  6. Fresh Cap 

  7. Chaos and Pain MUSH-TEN 

  8. Boku 

  9. Transparent Labs 

  10. Quality of Life AHCC® 

  11. The Raw Botanics Co

  12. Plant People WonderDay 

  13. Mushroom Revival 

  14. Live Conscious 

  15. Vital Plan Adaptogen 

  16. Rasa Magnificent 

  17. Sunwarrior Be Well 

  18. Real Mushrooms 5 Defenders 

  19. Cure Mushrooms 

  20. Clinical Effects Mushroom 

  21. Medterra Wellness 

  22. Four Sigmatic 

  23. NOW Cordyceps 

  24. Your Super Magic 

  25. ONNIT Shroom 

  26. New Chapter Superfood Mushroom Lion’s Mane Blend

  27. Ancient Nutrition Lion’s Mane Mental Clarity and Concentration DR

  28. Ryze Mushroom Coffee

  29. Freshcap Lion’s Mane Capsules

Who should take lion's mane supplements? 

Lion's mane supplements are suitable for anyone looking to promote overall health, mental clarity, and focus. Research suggests that they may be particularly beneficial for people with cognitive decline, including those suffering from Alzheimer's disease or dementia. Additionally, lion's mane supplements may help improve memory and learning abilities in healthy individuals. 

They have also been found to have anti-inflammatory properties and have been used to treat depression, anxiety, ulcers, and other digestive issues. Lion's mane is an all-natural supplement with minimal side effects and is generally safe for most people when taken as directed. However, it can interact with certain medications so you should always talk to your doctor before taking any new supplement. Taking lion's mane supplements could be a great way to support your overall health and well-being. 

If you are considering taking lion's mane supplements, it is important to discuss any potential risks or interactions with a healthcare provider. You should also consider the quality of the supplement when selecting one. Look for products that contain pure mushroom powder and have been tested for safety and potency by an independent laboratory. Finally, follow the dosage recommendations on the label and don’t take more than recommended unless otherwise advised by your doctor. By doing so, you can ensure that you get the most out of your lion's mane supplement and experience its many benefits without any unnecessary risks or side effects. 

1.     Elm & Rye Mushroom Complex 


Image courtesy Elm & Rye 

Over the past decade, mushrooms such as Reishi, Chaga, Cordyceps, Lion's Mane, and Turkey Tail have risen in popularity. For thousands of years, they have been used by Traditional Chinese Medicine practitioners and traditional healers across cultures to promote health and well-being.

In Ancient Greece, mushrooms were revered for their potent anti-inflammatory properties. Similarly, First Nations people implemented mushroom treatments to heal wounds. Nowadays, as Western research backs up the veracity of these claims and confirms that it is caused by a specific chemical pathway, mushrooms are proving themselves to be even more invaluable with every passing day.

Discover the unbelievable advantages of consuming mushrooms - all consolidated into one nutritious and delicious gummy or capsule: Elm & Rye's Mushroom Complex! This unique blend is crafted to provide maximum nourishment by leveraging the different benefits of various mushroom varieties.

2.    BATCH Brain Boost Mushroom Gummies

BATCH's Brain Boost Mushroom Gummies offer a number of potential benefits for brain health and cognitive function. These gummies contain a unique blend of Lions Mane Mushroom, Cordyceps, Reishi, Ginger Root, and Vitamin B. Each of these ingredients has been linked to various brain-boosting effects.

Lions Mane Mushroom has been shown to promote the growth of brain cells and improve cognitive function. BATCH's Lions Mane Mushroom Gummies are made with an 8:1 dual extract of Lions Mane Mushroom, which offers a higher level of potency and effectiveness than standard mushroom supplements. This dual extract process involves using both water and alcohol to extract the beneficial compounds from the mushroom, resulting in a more concentrated and bioavailable form of the active ingredients.

This 8:1 dual extract of Lions Mane Mushroom is rich in compounds called beta-glucans and hericenones, which have been linked to various cognitive benefits, including improved memory and focus, as well as reduced inflammation and oxidative stress. BATCH’s delicious wild berry formula offers a tasty way to enjoy one of the best brain boosting supplements on the market.

3.     Perpetua Life 

Image courtesy Perpetua Life

Perpetua Life Lion's Mane Gummies offer an easy and delicious way to get the benefits of this medicinal mushroom. This unique blend contains Lion's Mane, a mushroom that has been used for centuries by Traditional Chinese Medicine practitioners and traditional healers across cultures to promote health and well-being. 

Enjoy the anti-inflammatory properties of Ancient Greece while experiencing the powerful nourishment from First Nations people with each bite! Get maximum benefit from this potent supplement in every gummy - designed to support a stronger immune system and provide overall vitality for your body.

4.     Stonehenge Health 

Image courtesy Stonehenge Health 

Stonehenge Health's Dynamic Mushrooms are a powerful dietary supplement formulated to bring the benefits of various mushrooms into one convenient capsule. Leveraging potent anti-inflammatory compounds from Ancient Greek and First Nations sources, this unique blend combines Reishi, Chaga, Cordyceps, Lion's Mane, and Turkey Tail to provide maximum nourishment for your immune system. 

With every serving of Stonehenge Health Dynamic Mushrooms, you can enjoy unbeatable advantages that support strong health and well-being. This delicious and nutritious supplement is designed so that you can easily reap the numerous benefits of consuming mushrooms without having to buy them individually or prepare them yourself.

5.     Wild Foods Co 

Image courtesy Wild Foods Co 

Unmistakable in its distinctiveness, the Lion's Mane stands out among other mushrooms due to its mane-like appearance. With no cap or stem, this unique mushroom consists of long spines that droop down like a tousled mop of hair.

For centuries, Chinese Medicine has prescribed the lion's mane mushroom for digestive ailments as well as to enhance immunity. Upholding its traditional reputation, modern studies have supported this fungi's potential anti-inflammatory and antibacterial effects - playing a key role in building up our body’s defenses!

Lion's mane has been gaining immense popularity in the mental performance industry as it displays tremendous effects on improving brain function. The consumption of Lion’s mane is said to augment NGF levels in the brain, a key protein responsible for facilitating nerve cell activity.

6.     Fresh Cap Ultimate 

Image courtesy Fresh Cap 

Fresh Cap's Ultimate Mushroom Complex is an all-encompassing dietary supplement that delivers the benefits of various mushrooms in one convenient capsule. Combining anti-inflammatory compounds from Ancient Greek and First Nations sources, this unique blend contains Reishi, Chaga, Cordyceps, Lion's Mane, and Turkey Tail to provide maximum nourishment while supporting a stronger immune system.

Enjoy the unbeatable advantages of consuming mushrooms with every serving of this delicious and nutritious supplement. Fresh Cap's Ultimate Mushroom Complex is designed to help promote health and well-being while providing overall vitality for your body. Try it today and experience the powerful benefits of mushrooms!

7.     Chaos and Pain MUSH-TEN

Image courtesy Chaos and Pain 

Chaos and Pain's MUSH-TEN is a powerful 10-in-1 mushroom complex dietary supplement formulated to bring the benefits of various mushrooms into one convenient capsule. Combining anti-inflammatory compounds from Ancient Greek and First Nations sources, this unique blend contains Reishi, Chaga, Cordyceps, Lion's Mane, and Turkey Tail as well as five additional mushroom varieties to provide maximum nourishment while supporting a stronger immune system.

8.     Boku 

Image courtesy Boku 

Revitalize drained systems of the body while balancing overactive ones with this wild-crafted organic adaptogenic blend, supercharging energy and performance. 

This product is made from the fruiting bodies of fungi, and it's full of essential nutrients like vitamins, minerals, polysaccharides, beta-glucans, and antioxidants. It also contains secondary metabolites and various types of carotenoids and polyphenols to provide a robust combination for optimal health.

This brand's team collaborates with their farmers to create a unique, secret blend of ingredients which are then put through steam extraction processes that enhance its bioavailability more than any other products on the market.

9.     Transparent Labs 

Image courtesy Transparent Labs 

Transparent Labs' Shroom Stack is an all-in-one mushroom blend that combines seven of the most powerful mushrooms known to science into one convenient serving. This blend contains Lion's Mane, Chaga, Cordyceps, Maitake, Shiitake, Reishi, and Turkey Tail - each with its own individual benefits for health and well-being.

As one of the best mushroom supplements on the market, Shroom Stack contains no artificial ingredients, fillers, or binders and is crafted in an FDA cGMP-certified facility. With its potent combination of anti-inflammatory compounds from Ancient Greek and First Nations sources, this unique blend offers maximum nourishment while supporting a stronger immune system. Try it today and experience the powerful benefits of mushrooms.

10.  Quality of Life AHCC® 

Image courtesy Quality of Life 

AHCC® is a powerful, scientifically-backed and easily absorbed proprietary mushroom extract that boosts the body's immunity. When taken daily at a dose of 3g, it has been proven to provide superior immune support for cells throughout the entire body.

11.  The Raw Botanics Co

Image courtesy The Raw Botanics 

RISE Softgels from The Raw Botanics Co are formulated with natural, high-potency extracts of Chaga and Cordyceps mushrooms that have been sustainably harvested. This unique blend provides a range of benefits to support health and vitality, including improved cognitive function, energy, libido, and overall well-being.

Chaga is a powerful superfood mushroom that contains antioxidants, vitamins, minerals, and polysaccharides such as beta-glucans that are known to help boost the immune system. This product also contains Cordyceps to provide additional support for energy levels and mental clarity.

12.  Plant People WonderDay 

Image courtesy Plant People 

Plant People's WonderDay Mushroom Gummies are a delicious and convenient way to bring the benefits of mushrooms into your daily routine. These gummies contain a blend of five different mushrooms that have been sustainably harvested, including Chaga, Reishi, Lion's Mane, Cordyceps, and Turkey Tail.

13.  Mushroom Revival 

Image courtesy Mushroom Revival 

Experience the power of nature in just 10 seconds. Unlock your super brain power and amplify your health with functional mushrooms that won't get you high! Albert Einstein would be envious of this simplified method for achieving maximum results - directly from the earth to your brain. A few squeezes and sips can unlock a world of possibilities!

14.  Live Conscious 

Image courtesy Live Conscious 

Boost your mental and physical performance with Beyond Brew from Live Conscious. This delicious, energizing blend of mushrooms, herbs, greens, and adaptogens is designed to support cognitive function, focus, energy levels, mood stability, and stress management. 

With its unique combination of powerful ingredients like chaga mushrooms, ashwagandha root extract, green matcha, and moringa leaf extract, Beyond Brew is the perfect way to start your day. Enjoy as a hot or iced tea for an instant boost of energy - any time of day!

15.  Vital Plan Adaptogen 

Image courtesy Vital Plan 

With Adaptogen Recovery, you can be sure that your body's hormone and immune systems are in balance to handle any of life's demands. Our exclusive blend of adaptogenic herbs will help counteract the stressors that come with strenuous activities, all-nighters at work, or other pressures - so you can move through life feeling supported and resilient.

Not only do these herbs promote balance and harmony in your microbiome - the thousands of diverse bacteria that inhabit your body - but also, their well-being is essential for yours. After all, without a healthy microbiome, you cannot be truly healthy either!

16.  Rasa Magnificent 

Image courtesy Rasa 

Rasa's Magnificent Mushrooms blend is a carefully curated mix of five synergistic mushrooms that have been sustainably harvested and combined to power up your immune system. This unique blend works to nourish, replenish, and support the natural healing process while providing essential nutrients for optimal health and wellness. 

These potent mushrooms are fortified with vitamins, minerals, antioxidants, and polysaccharides. Together they work to provide relief from inflammation, boost energy levels, and support the body's natural defenses against disease. Enjoy this delicious blend in your morning smoothie or tonic for added health benefits.

17.  Sunwarrior Be Well Organic 

Image courtesy Sunwarrior

Organic Mushrooms harness an impressive concentration of antioxidants, which have the capacity to enhance your body's defenses against physical, chemical, and biological stressors. In addition to this incredible capability for protection from damaging conditions associated with stress, organic mushrooms can also help restore any damage that has already occurred.

18.  Real Mushrooms 5 Defenders

Image courtesy Real Mushrooms 

Real Mushrooms 5 Defenders Organic Mushroom Complex is an easy-to-use, comprehensive blend of five powerful mushrooms that provide a synergistic combination of mycelium and fruiting bodies. This unique blend supports your immune system, cognitive performance, cardiovascular health, and energy levels for overall well-being.

19.  Cure Mushrooms 

Image courtesy Cure Mushrooms 

Cure Mushrooms 14 Mushroom Blend Gummies are the perfect on-the-go snack for those looking to get their daily dose of mushrooms. This delicious mushroom blend features fourteen organic species, including Chaga, Reishi, Lion's Mane, Cordyceps, and Turkey Tail. Enjoy as a tasty treat or an energizing snack to fuel your body and mind.

20.  Clinical Effects 

Image courtesy Clinical Effects 

Clinical Effects Mushroom Formula 10 Extract is a potent blend of ten medicinal mushrooms that have been carefully formulated to provide powerful health-supporting benefits. This unique and comprehensive formula contains healing compounds like beta-glucans, enzymes, antioxidants, and polysaccharides that work together to support your cognitive performance, energy levels, blood sugar balance, and immune system. Enjoy this formula as a daily supplement for optimal health and well-being.

21.  Medterra Wellness

Image courtesy Medterra 

Medterra's Wellness Capsules are a powerful blend of six medicinal mushrooms that have been sustainably sourced and processed to provide superior health benefits. This blend features reishi, shiitake, maitake, cordyceps, lion’s mane, and turkey tail - all in one convenient capsule.

22.  Four Sigmatic 

Image courtesy Four Sigmatic 

Four Sigmatic's Mushroom Blend Coffee is the perfect way to start your day with a powerful dose of health-promoting mushrooms. This unique blend combines organic coffee with five different strains of medicinal mushroom extract for an energizing cup that supports your focus, energy levels, and cognitive performance.

23.  NOW Cordyceps 

Image courtesy NOW 

NOW Cordyceps 750 mg Veg Capsules provide a powerful dose of one of the most beneficial medicinal mushrooms available. This unique blend works to support energy levels, mental clarity, immune system health, and overall well-being. Enjoy this easy-to-take capsule for an added boost of nourishment throughout the day.

24.  Your Super Magic Mushroom 

Image courtesy Your Super Magic 

Your Super Magic Mushroom Mix is a delicious blend of four adaptogenic mushrooms – chaga, reishi, lion’s mane, and cordyceps. This powerful mix works to support the body’s natural defenses against stress and fatigue while providing essential nutrients for optimal health and wellness.

25.  ONNIT Shroom 

Image courtesy Onnit 

Shroom Tech® SPORT is an ideal supplement for anyone looking to maximize their energy output. Its adaptogenic compounds can help increase your exercise volume, improve aerobic performance, and boost energy utilization. 

Adults should take four capsules 45 minutes before exercising or competing - you can also consume these as needed for a quick burst of energy – preferably on an empty stomach. Please note that the maximum recommended intake in any 24-hour period must not exceed six capsules.

26.New Chapter Superfood Mushroom Lion’s Mane Blend

Image courtesy New Chapter 

Improve your focus and mental clarity with our specially formulated brain supplement! These top-notch nootropic mushrooms, featuring organic Lion's Mane, promote cognitive functioning and concentration. Ready to excel in work or school? Get prepared to put forth your best intellectual effort - this supplement will help you do just that!

Keep your mind sharp and alert for studying, working, or playing with the full-spectrum organic Superfood Lion's Mane. With only 2 capsules daily of this nootropic mushroom blend, you'll enjoy improved cognition and focus!

27.Ancient Nutrition Lion’s Mane Mental Clarity and Concentration DR

Image courtesy Ancient Nutrition 

Forge focus, clarity, and calm with the only USDA Certified Organic mushroom tablets out there these days. Ancient Nutrition has combined organic lion's mane and ashwagandha to help keep you sharp, centered, and in control of your day.

28.Ryze Mushroom Coffee

Image courtesy Ryze 

Start your day off right with Ryze’s Mushroom Coffee! Enjoy all the benefits of a traditional cup of coffee - an energizing and tasty beverage - but with the added benefit of medicinal mushrooms. This unique blend provides support for focus and concentration, energy levels, and cognitive performance.

29.Freshcap Lion’s Mane Capsules

Image courtesy Freshcap 

Tired of brain fog? Say hello to Lion's Mane, the "brain mushroom" that offers clarity and focus. With these convenient easy-to-use capsules, you can get maximum mental power wherever life takes you!


In conclusion, Lions Mane is an incredibly potent medicinal mushroom that offers numerous health benefits. Lions Mane supplements have become increasingly popular, and according to recent statistics, the global mushroom supplements market size is projected to reach USD 7.3 billion by 2027. When looking for the best Lions Mane supplement, it is essential to consider the quality and purity of the product. Look for supplements that are made from high-quality mushrooms and are tested for heavy metals and other contaminants. Lions Mane supplements have been shown to improve cognitive function, memory, and focus. They have also been linked to reduced inflammation, improved heart health, and reduced anxiety and depression symptoms. When choosing a Lions Mane supplement, consider whether you prefer capsules, powders, or liquid extracts. Some supplements may also contain additional ingredients, such as other mushrooms or adaptogenic herbs. It's important to note that supplements are not a substitute for a healthy diet and lifestyle. Additionally, it's crucial to consult with a healthcare professional before taking any new supplements, especially if you have underlying health conditions. Overall, Lions Mane supplements can be an excellent addition to a healthy lifestyle. By choosing a high-quality product and incorporating it into a balanced diet, you can experience the numerous health benefits of this powerful medicinal mushroom.

More From Discover
Recommendations From Our Store
Shop Now
Stay Curious
Our List

Sign up for our weekly science updates.

To The Magazine

Save up to 40% off the cover price when you subscribe to Discover magazine.

Copyright © 2023 Kalmbach Media Co.