15 Best Anxiety and Stress Relief Pills in 2023

By Amber Smith
Jun 3, 2023 4:00 AMJun 3, 2023 7:58 PM
Penguin CBD Gummies


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Each day we face endless stressors and anxiety-causing situations. While stress may be part of everyday life, it’s not something that you should just live with. Being in a constant state of fight-or-flight mode can have a lasting impact on your overall health. High cortisol levels have been linked to an increased risk of all sorts of health conditions, including diabetes, obesity, depression, fatigue, and gastrointestinal issues.

Though it may be impossible to avoid stress altogether, there are many things you can do to minimize its effects. Below you’ll find a list of the 15 best anxiety and stress relief pills in 2022. These products are specially formulated with proven ingredients that help your body to better manage stress while also supporting a happy, calm mood.

Keep reading to learn more about each of these anti-stress and anti-anxiety supplements so that you can find one that best meets your needs.

1. Penguin CBD Gummies

Anxiety and stress relief has never tasted so good. Penguin CBD Gummies are made with high quality CBD isolate that’s sourced from USA grown hemp. These sweet, sour, and tangy gummies provide 10mg of CBD each, which is an optimal dose for daily support.

CBD is well-known for its ever-growing list of therapeutic benefits. Penguin CBD Gummies not only alleviate stress and anxiety, they can also ease daily aches and pains, improve sleep quality, and boost your mood.

Chew your way to stress-free days with delicious Penguin CBD Gummies.

2. Everest Delta-8 Gummies

Let stress and anxiety float away while drifting into a mellow high by adding Everest Delta-8 Gummies to your daily regimen. These vegan, non-GMO gummies are enriched with delta-8 THC, a compound that’s known for creating a calming high that soothes your physical and mental well-being.

Each gummy is packed with 20mg of potent delta-8 THC. Everest Delta-8 Gummies are available in three great flavors: Blue Raspberry, Peach, and Watermelon. Enjoy stress-relief on-the-go with these soft fruity chews.

3. Elm & Rye Melatonin

Anxiety and stress impact nearly every aspect of your health. If daytime worries are causing you to lose sleep at night, Elm & Rye Melatonin can help. These melatonin-infused gummies were formulated by a team of world-class researchers that know the importance of sleep quality and quantity. Each chew provides an optimal dose of melatonin that helps you to fall asleep and stay asleep.

Research has also found that melatonin may also reduce stress and anxiety. Better sleep means a healthier you on the inside and out. Get the best sleep of your life with a nightly dose of Elm & Rye Melatonin.

4. Primal Harvest Primal Stress Relief

Enjoy a sense of calm and relaxation along with a balanced, uplifted mood with Primal Harvest Primal Stress Relief. This stress-relieving supplement also supports focus, memory, and sleep. Each capsule is packed with an optimal dose of L-theanine, rhodiola rosea, ashwagandha, and vitamin B6 to help you feel your best from head to toe.

Primal Harvest Primal Stress Relief is gluten-free, soy-free, and dairy-free. For best results, take one capsule a day.

5. Hello Bello Adult Stress Relief Gummies

Managing your stress and anxiety has never been so tasty! Hello Bello Adult Stress Relief Gummies are formulated with the powerful ancient adaptogen ashwagandha. This herb has been used for thousands of years due to its ability to reduce stress and support nervous system function.

Hello Bello Adult Stress Relief Gummies are also infused with vitamins B6 and B12, which boost immunity while supporting healthy energy levels.

6. Goli Ashwagandha Gummies

Unwind, restore, and relax, even after the most stressful day with Goli Ashwagandha Gummies. These mixed berry gummies are infused with KSM-66 ashwagandha, which has powerful anxiety and stress relieving properties. Not only do these gummies reduce stress, they promote relaxation and improve your sleep quality.

Goli Ashwagandha Gummies are non-GMO, vegan, gluten-free, and are made without gelatin. Support your physical and mental health and performance with just two gummies twice a day.

7. HUM Big Chill

Sit back, relax, and unwind with HUM Big Chill. These capsules are made with powerful rhodiola rosea extract, which works to fight against the signs of size while also supporting the body’s ability to cope with anxiety and daily worries.

Enhancing your calm and focus is as simple as taking one capsule a day. HUM Big Chill is non-GMO, gluten-free, and is made without any artificial colors or sweeteners. This supplement is also lab tested for purity and potency.

8. Garden of Life Dr. Formulated Stress Relief Gummies

Manage stress and maintain a positive all day long with Garden of Life Dr. Formulated Stress Relief Gummies. These berry citrus flavored gummies are made with a blend of lavender and L-theanine to promote calmness. These time-tested ingredients also optimize energy levels while minimizing fatigue.

Getting the most out of your day has never been more delicious. For best results take two Garden of Life Dr. Formulated Stress Relief Gummies a day.

9. For the Biome Stress Therapy

Elevate your daily cup of tea with For the Biome Stress Therapy. These tea bags are infused with seven potent flowers that are proven to lower stress and anxiety while supporting mental wellbeing. This supplement also engages the vagus nerve to boost gut and brain health. 

Each serving offers a precise dose of calendula, rose, saffron, elderflower, chamomile, and passionflower. By adding For the Biome Stress Therapy to your daily regimen, you'll experience increased mental clarity, higher levels of energy, and increased resilience to stress and anxiety.

10. Olly Goodbye Stress

With Olly Goodbye Stress Gummies, your days will be filled with nothing but good vibes. These delicious chews are formulated with everything your mind and body need to stay cool, calm, and collected. Each serving packs an optimized dose of lemon balm, GABA, and L-theanine to keep stress and anxiety at bay.

Olly Goodbye Stress Gummies offer a delicious berry verbena flavor that you can enjoy any time of day. The best part is that these gummies work in as little as 30 minutes to support a relaxed mind while fighting against the effects of stress and anxiety.

11. Vital Proteins Feeling Zen

Reach your daily zen with Vital Proteins Feeling Zen. Enjoy natural calmness and relaxation with a potent blend of ashwagandha, GABA, magnesium, and L-theanine. These capsules nourish your inner peace so that you can approach each day with mental clarity and calmness.

With your stress and anxiety levels balanced, you'll sleep better at night and wake up feeling refreshed and ready to take on the day. For best results take two Vital Proteins Feeling Zen capsules daily.

12. Gaia Daily Wellness Stress Response

Help your body better adapt to and cope with stress while uplifting your mood with Gaia Daily Wellness Stress Response. This herbal supplement is made with a blend of ashwagandha, holy basil, rhodiola, oats, and schisandra. If you're feeling run down mentally and physically, these capsules can give you a much needed boost.

Gaia Daily Wellness Stress Response are made with premium ingredients sourced from around the globe. They're vegan, gluten-free, and don't contain any dairy or soy ingredients. This supplement is also purity-tested, which means you can take them with total peace of mind.

13. Nature Made Wellblends Stress Relief Gummies

Kick stress and anxiety to the curb with delicious Nature Made Wellblends Stress Relief Gummies. These strawberry-flavored gummies are made with a scientific blend of L-theanine and GABA that provides stress-relief in an hour or less. Enjoy them anywhere at any time, whether you're at work, at home, or on the go.

No matter what the day brings, you can face it with Nature Made Wellblends Stress Relief Gummies. These gummies provide a sense of calm and peace without any gluten or high-fructose corn syrup.

14. JSHealth Anxiety + Stress Formula

Anxiety, stress, and everyday worries are no match for JSHealth Anxiety + Stress Formula. This supplement is formulated with a blend of passionflower, ashwagandha, B vitamins, and vitamin C to help you feel great. Minimize symptoms of anxiety while balancing your mood and supporting your body's ability to adapt to stress with just two tablets a day.

JSHealth Anxiety + Stress Formula provides everything your mind and body need. This supplement is made without gluten, dairy, sugar, or nuts. It's also vegan and non-GMO.

15. BrainMD Everyday Stress Relief

There’s nothing worse than a frazzled brain and nerves. Enjoy mental calmness with no drowsiness along with a positive mood and improved mental focus with BrainMD Everyday Stress Relief. This daily stress relief supplement is made with a premier blend of five natural compounds that ease anxiety so that you can feel your best.

Enjoy a tranquil mind and body with the power of taurine, L-theanine, holy basil extract, magnesium, and Relora powder. Together these ingredients reduce worry and nervousness while minimizing cortisol.

Are stress relief pills safe?

Yes and no. While all of the anxiety and stress relief pills on our list are safe, this can’t be said for every supplement that’s on the market. The fact is that the supplement industry is under-regulated, which means that products are marketed and sold on false pretenses.

Some may be created using low quality ingredients while others may forgo testing, which means that the purity, potency, and doses aren’t confirmed. Before buying any supplement, be sure to thoroughly research it or buy products that are researched and reviewed, like the 15 above.

The good news is that most anxiety relief products are made using a blend of vitamins, minerals, and natural compounds like herbs and botanicals. Generally speaking, these ingredients are safe and rarely cause any adverse side effects.

Other ways to reduce your stress and anxiety

Supplements are just one of the many ways that you can reduce your stress and anxiety. In fact, combining other stress-relieving tactics with the right supplement can have an immense impact on your physical and mental well-being.

Here are some other ways you can ease your stress and anxiety on a daily basis.

Know your limits

We often place undue stress on ourselves by not knowing when to say “no.” While you may want to do it all, the reality is that you can't. Learning when to say no and prioritizing your to-do list also means reducing your stress and anxiety. Saying yes may keep the peace, but at what cost? Don't let an overly full plate be the cause of poor mental health.

Get (and stay!) active

Any form of physical activity, whether it's swimming, running, or riding a bike, serves as a great stress reliever. Exercise increases endorphin levels and other natural feel good hormones.

Physical activity helps you to refocus your mind on each movement, and in turn, daily frustrations fade away to the back of your mind.

Eat a wholesome diet

You are what you eat. A diet filled with processed foods that provide little to no nutritious values will have a negative impact on your well-being. Revamp your diet, and your mood, by eating plenty of fruits, vegetables, lean proteins, whole grains, and legumes.

Focus on your breathing

Taking deep, slow breaths lowers your heart rate and blood pressure. There are many different breathing techniques that you can try, such as breathing through one nostril at a time, to ease anxiety. Deep breathing exercises balance the mind and body and may be as effective as acupuncture.


Meditation is another great way to bring your mind and body back into alignment. During these sessions, you can calm a racing mind and quiet all of the thoughts running through your head. Meditating promotes a sense of peace, calm, and balance.

Head outdoors

The combination of fresh air and sunshine can have a huge impact on your mood and stress levels. If you're feeling overwhelmed or are struggling to concentrate, head outdoors and experience an immediate mental and emotional boost.

Laugh more

There's nothing better than a good laugh. Laughing lightens your mental load and cools your body's response to stress. So whether you choose to tell a few jokes or watch a funny comedy series, what's most important is that you get in a few laughs here and there.

Kick unhealthy habits to the curb

Excessive drinking, smoking, and any kind of drug use not only harm your health, they worsen high stress and anxiety levels. While many people drink and smoke cigarettes to ease stress, these habits have serious long-term health impacts.

Final thoughts

Don’t let stress and anxiety take the joy out of your life. No matter if you’re facing work at home, at work, or both, there are many things you can do to take back control. With one of the 15 best anxiety and stress relief pills in 2022, you can minimize your worries and start feeling like the old you again.

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