Register for an account

X

Enter your name and email address below.

Your email address is used to log in and will not be shared or sold. Read our privacy policy.

X

Website access code

Enter your access code into the form field below.

If you are a Zinio, Nook, Kindle, Apple, or Google Play subscriber, you can enter your website access code to gain subscriber access. Your website access code is located in the upper right corner of the Table of Contents page of your digital edition.

Health

Eugenics, the 100 year cycle

Gene ExpressionBy Razib KhanNovember 12, 2012 10:50 AM

Newsletter

Sign up for our email newsletter for the latest science news

The Chronicle of Higher Education has a piece out by Nathaniel Comfort, The Eugenic Impulse. I would just like to offer that to a great extent we already live in the second age of eugenics. The high frequency of abortions of fetuses which come back positive for Down syndrome is well known. But it seems possible that we'll be able to reduce the frequency of many Mendelian diseases as well. Basically those ailments which are due to a major mutation of large effect and high penetrance (i.e., you have the mutation, you have the disease). A major goal which we're very far from though is the ability to select for quantitative traits. There are technical hurdles, both tactical and strategic, here. The major issue is that there are simply too many variants for one to be able to select a 'perfect' genetic profile. Those who've talked to me know my response in this domain: select for low mutational load. High coverage fetal whole genome sequencing would do that. The marketing pitch for this writes itself: imagine you, but bright of mind, and beautiful of face!

    2 Free Articles Left

    Want it all? Get unlimited access when you subscribe.

    Subscribe

    Already a subscriber? Register or Log In

    Want unlimited access?

    Subscribe today and save 70%

    Subscribe

    Already a subscriber? Register or Log In