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Double feature: A puppy trapped in a cyst and a tumor that looks like a Basset hound.

Discover the intriguing Mucus Retention Cyst of the Vocal Cord, humorously resembling a puppy in Reinke's space.

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Like a child looking at clouds, when pathologists look at tissue samples too long, apparently they start to see shapes in them. For some reason puppies are especially popular – we’ve previously posted about a tumor shaped like a puppy, and below are two more examples. I guess when your job is diagnosing diseases all day, you find humor wherever you can?

Puppy in a cyst: "I'm trapped! Help please!".

"A cyst is present in Reinke's space in a true vocal cord biopsy.It contains mucus inspisated in a shape resembling a puppy (Figure 1). The cyst is lined by columnar epithelium (Figure 2). We diagnosed it as a Mucus Retention Cyst of the Vocal Cord. Mucus retention cyst of the true vocal cord arises from a blocked mucus-producing gland in this area."

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A Well-Differentiated Squamous Cell Basset Hound

"A sad-looking basset hound invading the dermis."

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Figure 1. A well-differentiated, but sad-looking squamous cell Basset hound invading the dermis

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